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Structure of 1820885-11-7
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Methyl 5-bromo-3-fluorothiophene-2-carboxylate features a thiophene core bearing bromo and fluoro substituents at the 5- and 3-positions, respectively, with a methyl ester at C2. This electron-deficient heterocycle integrates readily into cross-coupling reactions, enabling efficient access to complex functionalized building blocks in medicinal chemistry and materials synthesis.
Methyl 5-bromo-3-fluorothiophene-2-carboxylate serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its bromo substituent. The fluorine atom enhances metabolic stability and modulates electronic properties, while the ester group provides a handle for further functionalization. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to substituted thiophene scaffolds relevant to pharmaceutical and agrochemical development.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: