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CS-W001157 4
Total: USD 88.00

2-(Tert-butyl)pyrimidine-4,5-diamine

  • CAS No. 18202-78-3

  • Cat. No. CS-0582649
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(Tert-butyl)pyrimidine-4,5-diamine|CS-0582649

Structure of 18202-78-3

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General Information

  • CAS No. 18202-78-3
  • Cat. No. CS-0582649
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄N₄
  • Molecular Weight 166.22
  • Synonym(s) 2-tert-butylpyrimidine-4,5-diamine
  • SMILES NC1=NC(C(C)(C)C)=NC=C1N

Synthesis

  • Route1
    • 2-(tert-Butyl)-5-nitropyrimidin-4-amine|CS-0734331
      70227-51-9
    • ~99%
    • 2-(Tert-butyl)pyrimidine-4,5-diamine|CS-0582649
      18202-78-3

    References

    • SUNESIS PHARMACEUTICALS, INC. Patent: WO2006/65703 A1, 2006 ; Location in patent: Page/Page column 104 ; WO 2006/065703 A1
  • Route2

    References

    • Tielemans, Michel; Christophe, Daniel; Promel, Robert Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 705 - 708
  • Route3
    • 2-(tert-Butyl)-4-chloro-5-nitropyrimidine|CS-0154882
      70227-50-8
    • ~%
    • 2-(Tert-butyl)pyrimidine-4,5-diamine|CS-0582649
      18202-78-3

    References

    • Tielemans, Michel; Christophe, Daniel; Promel, Robert Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 705 - 708

Safety Information

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GHS Pictogram : N/A
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UN#: N/A
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Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   77.82
  • LogP   0.9385
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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