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CS-W001157 4
Total: USD 88.00

Pivalimidamide hydrochloride

  • CAS No. 18202-73-8

  • Cat. No. CS-W005597
  • Molecule weight136.62
  • Purity≥97%
  • MDL No.MFCD00051988

*For research and further manufacturing use only, not for direct human use.

Pivalimidamide hydrochloride|CS-W005597

Structure of 18202-73-8

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General Information

  • CAS No. 18202-73-8
  • Cat. No. CS-W005597
  • Purity ≥97%
  • MDL No. MFCD00051988
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃ClN₂
  • Molecular Weight 136.62
  • Synonym(s) Pivalamidine hydrochloride
  • SMILES CC(C)(C(N)=N)C.Cl

Description

Pivalimidamide hydrochloride serves as a stable, moisture-tolerant amide coupling reagent, enabling efficient peptide bond formation under mild conditions. This sterically hindered imidamide derivative facilitates rapid activation of carboxylic acids while minimizing racemization during synthetic workflows.

Application

Pivalimidamide hydrochloride serves as a stable, bench-ready amide surrogate for the efficient installation of pivaloyl groups in synthetic workflows. It functions as a mild acylating agent with excellent functional group tolerance and facilitates direct amidation without over-activation. Its crystalline form enables straightforward handling and purification, making it ideal for use in peptide synthesis, late-stage functionalization, and the construction of bioactive heterocyclic scaffolds requiring robust amide linkage stability.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.87
  • LogP   1.39027
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   0

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