AR antagonist 1 hydrochloride

Name: AR antagonist 1 hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1818885-55-0
Cat. No. CS-0137032
Purity≥98%
MDL No.MFCD30729667

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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AR antagonist 1 hydrochloride|CS-0137032

Structure of 1818885-55-0

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Description

AR antagonist 1 (hydrochloride) delivers potent and selective inhibition of the androgen receptor, enabling precise modulation in hormone-sensitive biological systems. This bench-stable compound features enhanced solubility in aqueous media, facilitating consistent performance across cell-based assays and in vitro studies.

Application

AR antagonist 1 (hydrochloride) serves as a well-characterized tool compound for studying androgen receptor signaling pathways. It functions as a potent, selective ligand that binds competitively to the androgen receptor’s ligand-binding domain, inhibiting downstream transcriptional activity. Its hydrochloride salt form enhances solubility and stability in aqueous buffers, enabling consistent performance in cell-based assays and in vitro binding studies. This compound facilitates mechanistic investigations into hormone-dependent cancer biology and supports screening campaigns targeting androgen-responsive systems.

General Information

CAS No. 1818885-55-0
Cat. No. CS-0137032
Purity ≥98%
MDL No. MFCD30729667
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₂₀Cl₂N₂O
Molecular Weight 315.24
Synonym(s) None
SMILES [H]Cl.N#CC1=CC=C(O[C@H]2C(C)(C)[C@H](N)C2(C)C)C=C1Cl

Computational Chemistry Data

TPSA 59.04
LogP 3.77418
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Chloride

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Fatty ring compounds Cyclobutane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

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AR antagonist 1 hydrochloride

CAS No. 1818885-55-0

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