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3-Aminooxetane-3-carbonitrile hydrochloride

  • CAS No. 1818847-73-2

  • Cat. No. CS-0051532
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Aminooxetane-3-carbonitrile hydrochloride|CS-0051532

Structure of 1818847-73-2

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General Information

  • CAS No. 1818847-73-2
  • Cat. No. CS-0051532
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇ClN₂O
  • Molecular Weight 134.56
  • Synonym(s) 3-AMINOOXETANE-3-CARBONITRILE HCL
  • SMILES Cl.NC1(COC1)C#N

Description

3-Aminooxetane-3-carbonitrile hydrochloride is a bench-stable, moisture-tolerant heterocyclic building block featuring a strained oxetane ring fused to an electron-deficient nitrile and primary amine. This combination enables direct incorporation into bioactive molecule scaffolds via nucleophilic substitution or conjugate addition, streamlining access to pharmacologically relevant architectures in medicinal chemistry workflows.

Application

3-Aminooxetane-3-carbonitrile hydrochloride serves as a versatile synthetic building block for constructing bioactive heterocycles, particularly in medicinal chemistry. Its oxetane ring imparts enhanced metabolic stability and improved solubility, while the nitrile and amine functionalities enable diverse downstream transformations. The hydrochloride salt ensures excellent bench stability and ease of handling, facilitating straightforward purification and compatibility with standard coupling reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.04
  • LogP   -0.34052
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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