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CS-W001157 4
Total: USD 88.00

Pregabalin lactam

  • CAS No. 181289-23-6

  • Cat. No. CS-0096516
  • Purity≥98%
  • MDL No.MFCD19217624

*For research and further manufacturing use only, not for direct human use.

Pregabalin lactam|CS-0096516

Structure of 181289-23-6

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General Information

  • CAS No. 181289-23-6
  • Cat. No. CS-0096516
  • Purity ≥98%
  • MDL No. MFCD19217624
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO
  • Molecular Weight 141.21
  • Synonym(s) None
  • SMILES O=C1NC[C@@H](CC(C)C)C1

Description

(S)-4-Isobutylpyrrolidin-2-one is a chiral pyrrolidinone scaffold featuring a stereodefined center and a hydrophobic isobutyl substituent. This configuration imparts enhanced selectivity in asymmetric synthesis, enabling efficient integration into bioactive molecules. The compound exhibits robust stability under standard bench conditions and facilitates streamlined access to complex nitrogen-containing architectures.

Application

(S)-4-Isobutylpyrrolidin-2-one serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its pyrrolidinone core exhibits excellent functional group tolerance and bench stability, facilitating downstream transformations such as alkylation, acylation, and reductive amination. The stereogenic center supports enantioselective synthesis, making it valuable for constructing complex scaffolds in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.1686
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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