Methyl 3-amino-7-chlorobenzo[b]thiophene-2-carboxylate

Name: Methyl 3-amino-7-chlorobenzo[b]thiophene-2-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 181283-33-0
Cat. No. CS-0448622
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 3-amino-7-chlorobenzo[b]thiophene-2-carboxylate|CS-0448622

Structure of 181283-33-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Methyl 3-amino-7-chlorobenzo[b]thiophene-2-carboxylate integrates a chlorinated benzo[b]thiophene core with an amino group at C3 and a methyl ester at C2, delivering a versatile scaffold for medicinal chemistry. The electron-donating amino moiety enhances reactivity in coupling reactions, while the chloro substituent provides a handle for further functionalization. This bench-stable compound enables efficient access to bioactive heterocycles under standard conditions.

Application

Methyl 3-amino-7-chlorobenzo[b]thiophene-2-carboxylate serves as a versatile building block for the synthesis of bioactive heterocycles, enabling direct functionalization at the amino and carboxylate positions. The chloro group provides a site for palladium-catalyzed cross-coupling, while the amine facilitates acylation or reductive alkylation. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step sequences targeting pharmaceutical scaffolds.

General Information

CAS No. 181283-33-0
Cat. No. CS-0448622
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₈ClNO₂S
Molecular Weight 241.69
Synonym(s) 3-Amino-2-carbomethoxy-7-chloro-benzthiophene
SMILES COC(=O)C1=C(C2=C(C(=CC=C2)Cl)S1)N

Computational Chemistry Data

TPSA 52.32
LogP 2.9235
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Benzothiophene compounds

Key Words

181283-33-0 sigma181283-33-0 manufacturer181283-33-0 price181283-33-0 structure181283-33-0 SDSbuy 181283-33-0181283-33-0 supplier181283-33-0 uses181283-33-0 molecular weightprice of 181283-33-0181283-33-0 chemical name formula of 181283-33-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 3-amino-7-chlorobenzo[b]thiophene-2-carboxylate

CAS No. 181283-33-0

Recommended Products