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CS-W001157 4
Total: USD 88.00

(S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride

  • CAS No. 181228-33-1

  • Cat. No. CS-W006152
  • Purity≥95%
  • MDL No.MFCD04973085

*For research and further manufacturing use only, not for direct human use.

(S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride|CS-W006152

Structure of 181228-33-1

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General Information

  • CAS No. 181228-33-1
  • Cat. No. CS-W006152
  • Purity ≥95%
  • MDL No. MFCD04973085
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₉ClN₂O₄
  • Molecular Weight 254.71
  • Synonym(s) None
  • SMILES O=C([C@H](CN)NC(OC(C)(C)C)=O)OC.Cl

Description

(S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride features a chiral α-amino acid scaffold with orthogonal protection: the amine is masked as a tert-butoxycarbonyl (Boc) group, while the carboxylic acid is esterified. This configuration enables selective deprotection and coupling in peptide synthesis workflows. The hydrochloride salt enhances solubility and handling stability under standard bench conditions.

Application

(S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride serves as a key chiral building block in peptide synthesis and medicinal chemistry. The protected amine and carboxylate functionalities enable orthogonal transformations, while the (S)-configuration ensures stereochemical fidelity in target molecules. Bench-stable and readily purified by crystallization, it facilitates efficient coupling reactions and downstream derivatization in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   0.4332
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   3

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