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N1,​N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide

  • CAS No. 1809289-04-0

  • Cat. No. CS-0128764
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N1,​N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide|CS-0128764

Structure of 1809289-04-0

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General Information

  • CAS No. 1809289-04-0
  • Cat. No. CS-0128764
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₂₄N₂O₂
  • Molecular Weight 420.50
  • Synonym(s) None
  • SMILES O=C(NC1=CC=C(C)C=C1C2=CC=CC=C2)C(NC3=C(C4=CC=CC=C4)C=C(C)C=C3)=O

Description

N1,N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide features two electron-rich biphenyl groups flanking a rigid oxalamide core, enabling strong π–π interactions and precise molecular recognition. This structure enhances solubility in organic media while maintaining thermal stability under standard conditions. The sterically hindered methyl substituents minimize unwanted aggregation, facilitating use in supramolecular assembly and coordination chemistry applications.

Application

N1,N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide serves as a robust bis-amide ligand in transition metal catalysis, enabling efficient C–C and C–heteroatom bond formations. Its sterically hindered aryl groups enhance solubility and stability under reaction conditions, while the oxalamide backbone provides strong coordination to palladium and nickel centers. This structure facilitates cross-coupling reactions with broad functional group tolerance and simplifies purification due to low volatility and thermal resilience.

Safety Information

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GHS Pictogram :
GHS No : GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H372-H411
Precautionary Statements : P260-P264-P273-P391-P501

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Computational Chemistry Data

  • TPSA   58.2
  • LogP   6.21464
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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