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CS-W001157 4
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Ethyl 4-bromothieno[2,3-c]pyridine-2-carboxylate

  • CAS No. 1809004-78-1

  • Cat. No. CS-0041155
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-bromothieno[2,3-c]pyridine-2-carboxylate|CS-0041155

Structure of 1809004-78-1

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General Information

  • CAS No. 1809004-78-1
  • Cat. No. CS-0041155
  • Purity ≥98%
  • MDL No. None
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrNO₂S
  • Molecular Weight 286.15
  • Synonym(s) None
  • SMILES O=C(C(S1)=CC2=C1C=NC=C2Br)OCC

Description

Ethyl 4-bromothieno[2,3-c]pyridine-2-carboxylate features a fused thienopyridine core with a bromine atom at the 4-position and an ethyl ester group at the 2-position. This electrophilic scaffold enables direct functionalization in cross-coupling reactions, serving as a key building block for bioactive heterocycles. The molecule exhibits excellent stability under standard conditions and facilitates efficient diversification in medicinal chemistry campaigns.

Application

Ethyl 4-bromothieno[2,3-c]pyridine-2-carboxylate serves as a versatile building block for the synthesis of thienopyridine-based heterocycles. The bromine substituent enables palladium-catalyzed cross-coupling reactions, while the ester group supports further functionalization. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to complex scaffolds relevant in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   3.2355
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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