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Structure of 1805287-23-3
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2-(Difluoromethyl)-5-iodopyridine features a difluoromethyl group at the 2-position and an iodine atom at the 5-position of the pyridine core. This electron-deficient heterocycle enables direct functionalization in cross-coupling reactions, offering high reactivity under mild conditions. The molecule combines enhanced stability with favorable solubility in common organic solvents, facilitating its use in medicinal chemistry and materials synthesis workflows.
2-(Difluoromethyl)-5-iodopyridine serves as a versatile building block for late-stage functionalization and cross-coupling reactions in medicinal chemistry. The difluoromethyl group imparts enhanced metabolic stability and modulates lipophilicity, while the iodopyridine moiety enables palladium-catalyzed couplings with broad functional group tolerance. Its bench-stable nature and compatibility with standard Suzuki, Stille, and Negishi protocols facilitate efficient construction of complex heterocyclic scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: