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1-Naphthyltrimethoxysilane

  • CAS No. 18052-76-1

  • Cat. No. CS-B0749
  • Purity≥97%
  • MDL No.MFCD03411254

*For research and further manufacturing use only, not for direct human use.

1-Naphthyltrimethoxysilane|CS-B0749

Structure of 18052-76-1

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General Information

  • CAS No. 18052-76-1
  • Cat. No. CS-B0749
  • Purity ≥97%
  • MDL No. MFCD03411254
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₆O₃Si
  • Molecular Weight 248.35
  • Synonym(s) Trimethoxy(1-naphthyl)silane; 1-Naphthyltrimethoxysilane
  • SMILES CO[Si](OC)(C1=C2C=CC=CC2=CC=C1)OC

Description

1-Naphthyltrimethoxysilane features a naphthyl group linked to a trimethoxysilyl moiety, enabling robust coupling to silica surfaces. This functional silane integrates seamlessly into surface modification protocols, delivering stable, hydrophobic interfaces ideal for chromatographic supports and sensor platforms.

Application

1-Naphthyltrimethoxysilane serves as a stable, bench-ready silyl protecting group for phenolic hydroxyls and facilitates efficient coupling in Si–O bond-forming reactions. Its naphthyl moiety provides enhanced solubility and spectral distinguishability, enabling straightforward purification and monitoring. Functions reliably in standard deprotection and cross-coupling workflows, offering robust utility in complex molecule synthesis and material functionalization.

Synthesis

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      1-Bromonaphthalene|CS-0017140
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    • In-stock
      1-Naphthyltrimethoxysilane|CS-B0749
      18052-76-1

    References

    • Bauer, Jonathan O.; Strohmann, Carsten Chemical Communications, 2012 , vol. 48, # 57 p. 7212 - 7214
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    • In-stock
      1-Naphthyltrimethoxysilane|CS-B0749
      18052-76-1

    References

    • DOW CORNING TORAY CO., LTD.; TANIGUCHI, Yoshinori; SUGIURA, Yasushi Patent: WO2013/100166 A1, 2013 ; Location in patent: Paragraph 0054 ;
  • Route3
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      703-55-9
    • ~%
    • In-stock
      1-Naphthyltrimethoxysilane|CS-B0749
      18052-76-1

    References

    • Sanin Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 1286,1287;engl.Ausg.S.1371

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   1.9249
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

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