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Structure of 180205-28-1
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1-(Aminomethyl)cyclobutanol features a cyclobutanol ring bearing a primary amine-functionalized methylene group, offering a rigid, sterically constrained scaffold ideal for medicinal chemistry. This configuration enables direct incorporation into bioactive molecules where conformational restriction enhances target affinity and metabolic stability.
1-(Aminomethyl)cyclobutanol serves as a versatile building block in medicinal chemistry, enabling the construction of saturated heterocyclic scaffolds through straightforward functionalization. Its pendant primary amine and hydroxyl groups offer orthogonal reactivity for selective derivatization, while the cyclobutane ring provides conformational rigidity beneficial for target engagement. The compound exhibits good bench stability and facilitates purification via standard chromatographic methods, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: