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Structure of 1801711-87-4
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This boronate-containing carboxylic acid integrates a hydroxylated oxaborole scaffold, offering enhanced stability and compatibility in cross-coupling reactions. The ortho-hydroxy group facilitates in situ transmetalation, while the carboxylic acid enables conjugation or derivatization under mild conditions.
1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-5-carboxylic acid serves as a stable, bench-ready boron-containing building block for Suzuki-Miyaura cross-coupling reactions. Its carboxylic acid and hydroxyl functionalities enable orthogonal derivatization and facilitate purification via standard chromatographic methods. The oxaborole core provides enhanced reactivity and thermal stability compared to traditional boronic acids, making it well-suited for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: