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Structure of 1799420-93-1
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2-Bromo-3-chloro-5-(difluoromethoxy)pyridine is a halogenated pyridine derivative featuring complementary reactive sites for cross-coupling and functionalization. The difluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the bromo and chloro substituents enable sequential Pd-catalyzed transformations. This scaffold integrates efficiently into complex heterocyclic architectures under mild conditions.
2-Bromo-3-chloro-5-(difluoromethoxy)pyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The difluoromethoxy group enhances metabolic stability and modulates lipophilicity, while the ortho-bromine facilitates selective functionalization. Bench-stable and compatible with standard purification methods, it functions reliably in late-stage diversification of heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: