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CS-W001157 4
Total: USD 88.00

Methyl 7-aminoheptanoate hydrochloride

  • CAS No. 17994-94-4

  • Cat. No. CS-W004807
  • Purity≥97%
  • MDL No.MFCD09029389

*For research and further manufacturing use only, not for direct human use.

Methyl 7-aminoheptanoate hydrochloride|CS-W004807

Structure of 17994-94-4

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General Information

  • CAS No. 17994-94-4
  • Cat. No. CS-W004807
  • Purity ≥97%
  • MDL No. MFCD09029389
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈ClNO₂
  • Molecular Weight 195.69
  • Synonym(s) None
  • SMILES Cl.O=C(OC)CCCCCCN

Description

Methyl 7-aminoheptanoate hydrochloride features a primary amine group flanked by a methoxy ester, enabling direct functionalization in peptide and macrocycle synthesis. This bench-stable derivative delivers enhanced solubility in polar solvents while maintaining reactivity under standard coupling conditions.

Application

Methyl 7-aminoheptanoate hydrochloride serves as a versatile bifunctional building block in synthetic organic chemistry, enabling efficient access to γ-aminocarboxylate scaffolds. The primary amine and ester functionalities offer orthogonal reactivity for peptide coupling, lactam formation, and side-chain derivatization. Its crystalline hydrochloride salt enhances bench stability and simplifies purification, facilitating use in multi-step syntheses of bioactive molecules and heterocyclic intermediates.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      7-Aminoheptanoic acid|CS-W002042
      929-17-9
    • ~99%
    • In-stock
      Methyl 7-aminoheptanoate hydrochloride|CS-W004807
      17994-94-4

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 9 p. 2809 - 2812
  • Route2

    References

    • US6498172 B1, ;
  • Route3
    • null|null
      502-42-1
    • ~%
    • In-stock
      Methyl 7-aminoheptanoate hydrochloride|CS-W004807
      17994-94-4

    References

    • WO2011/91213 A2, ; WO 2011/091213 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.4904
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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