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CS-W001157 4
Total: USD 88.00

2-Amino-2-(4-chlorophenyl)ethan-1-ol

  • CAS No. 179811-64-4

  • Cat. No. CS-0173227
  • Purity≥97%
  • MDL No.MFCD09759235

*For research and further manufacturing use only, not for direct human use.

2-Amino-2-(4-chlorophenyl)ethan-1-ol|CS-0173227

Structure of 179811-64-4

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General Information

  • CAS No. 179811-64-4
  • Cat. No. CS-0173227
  • Purity ≥97%
  • MDL No. MFCD09759235
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀ClNO
  • Molecular Weight 171.62
  • Synonym(s) DL-Parachlorophenylglycine
  • SMILES OCC(N)C1=CC=C(Cl)C=C1

Description

2-Amino-2-(4-chlorophenyl)ethan-1-ol features a benzylic alcohol scaffold bearing a para-chlorophenyl group and a primary amine, enabling integration into chiral building blocks. This bench-stable, moisture-tolerant compound facilitates synthesis of bioactive intermediates in medicinal chemistry workflows.

Application

2-Amino-2-(4-chlorophenyl)ethan-1-ol serves as a key chiral building block in medicinal chemistry, enabling the synthesis of β-amino alcohol scaffolds via standard reductive amination or epoxide ring-opening protocols. Its pendant amine and hydroxyl groups exhibit excellent functional group tolerance, facilitating downstream derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring orthogonal reactivity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.3321
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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