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CS-W001157 4
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Triethoxy(isobutyl)silane

  • CAS No. 17980-47-1

  • Cat. No. CS-0151947
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Triethoxy(isobutyl)silane|CS-0151947

Structure of 17980-47-1

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General Information

  • CAS No. 17980-47-1
  • Cat. No. CS-0151947
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₄O₃Si
  • Molecular Weight 220.38
  • Synonym(s) Triethoxyisobutylsilane
  • SMILES CCO[Si](CC(C)C)(OCC)OCC

Description

Triethoxy(isobutyl)silane delivers a hydrolytically stable silane coupling agent with enhanced steric shielding from its branched isobutyl group. This structure enables efficient surface functionalization of inorganic substrates while maintaining compatibility with moisture-sensitive processes. The triethoxy moiety facilitates rapid condensation, forming durable Si–O–M bonds under mild conditions.

Application

Triethoxy(isobutyl)silane serves as a stable, bench-friendly silyl protecting group reagent, enabling selective protection of alcohols and amines under mild conditions. Its isobutyl substituent provides enhanced steric bulk and hydrolytic stability compared to simpler silanes, facilitating efficient deprotection with fluoride sources or mild acid. The triethoxy functionality ensures compatibility with standard silylation protocols, offering excellent functional group tolerance and ease of purification in complex molecule synthesis.

Synthesis

  • Route1
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      78-10-4
    • ~%
    • In-stock
      Triethoxy(isobutyl)silane|CS-0151947
      17980-47-1

    References

    • Zhurnal obshchei Khim. (russ.), , vol. 8, p. 558 - 562 C. II, , p. 3674 Si: MVol.C, 74, page 207 - 208
  • Route2
    • null|null
      78-10-4
    • null|null
      513-36-0
    • ~%
    • In-stock
      Triethoxy(isobutyl)silane|CS-0151947
      17980-47-1

    References

    • Zhurnal Obshchei Khimii, , vol. 8, p. 555 Chem. Zentralbl., , vol. 109, # II p. 3674
  • Route3
    • null|null
      78-10-4
    • null|null
      5674-02-2
    • ~%
    • In-stock
      Triethoxy(isobutyl)silane|CS-0151947
      17980-47-1

    References

    • Zhurnal Obshchei Khimii, , vol. 8, p. 555 Chem. Zentralbl., , vol. 109, # II p. 3674

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315
Precautionary Statements : P210-P264-P280-P302+P352-P362+P364-P370+P378-P403-P501

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   2.6908
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   8

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