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CS-W001157 4
Total: USD 88.00

(2-Isopropylpyridin-4-yl)boronic acid

  • CAS No. 1788062-08-7

  • Cat. No. CS-0336771
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Isopropylpyridin-4-yl)boronic acid|CS-0336771

Structure of 1788062-08-7

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General Information

  • CAS No. 1788062-08-7
  • Cat. No. CS-0336771
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂BNO₂
  • Molecular Weight 165.00
  • Synonym(s) (2-Isopropyl-4-pyridinyl)boronic acid
  • SMILES OB(C1=CC(C(C)C)=NC=C1)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The para-isopropylpyridine scaffold enhances solubility and stability, while the boronic acid group offers predictable reactivity and compatibility with diverse functional groups.

Application

(2-Isopropylpyridin-4-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced solubility and metabolic stability. The isopropyl group imparts favorable steric and electronic properties, improving reaction efficiency and product yield. Bench-stable and readily purified by recrystallization, it functions reliably in the synthesis of pharmaceutical intermediates and functionalized heterocycles.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.1152
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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