Methyl 5-bromo-2-chlorothiazole-4-carboxylate

Name: Methyl 5-bromo-2-chlorothiazole-4-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1784255-01-1
Cat. No. CS-0150906
Purity≥98%
MDL No.MFCD27922923

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 5-bromo-2-chlorothiazole-4-carboxylate|CS-0150906

Structure of 1784255-01-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1784255-01-1
Cat. No. CS-0150906
Purity ≥98%
MDL No. MFCD27922923
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃BrClNO₂S
Molecular Weight 256.50
Synonym(s) 5-Bromo-2-chloro-thiazole-4-carboxylic acid methyl ester
SMILES COC(=O)C1=C(Br)SC(=N1)Cl

Description

Methyl 5-bromo-2-chlorothiazole-4-carboxylate features a fused thiazole core with complementary halogen substituents at the 5- and 2-positions, enabling selective cross-coupling and functionalization. The methyl ester group provides enhanced solubility and reactivity in transition-metal-catalyzed transformations. This bench-stable, moisture-tolerant building block integrates efficiently into complex heterocyclic architectures under standard conditions.

Application

Methyl 5-bromo-2-chlorothiazole-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromo and chloro substituents. The methyl ester group facilitates downstream functionalization, while the thiazole core provides structural rigidity and electronic properties valuable in medicinal chemistry. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for modular synthesis of complex scaffolds.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 39.19
LogP 2.3456
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

1784255-01-1 sigma1784255-01-1 manufacturer1784255-01-1 price1784255-01-1 structure1784255-01-1 SDSbuy 1784255-01-11784255-01-1 supplier1784255-01-1 uses1784255-01-1 molecular weightprice of 1784255-01-11784255-01-1 chemical name formula of 1784255-01-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 5-bromo-2-chlorothiazole-4-carboxylate

CAS No. 1784255-01-1

Recommended Products