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Structure of 1783945-29-8
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This bench-stable, moisture-tolerant building block features a difluorinated piperidine core that enhances metabolic stability and membrane permeability. The hydrochloride salt form ensures excellent solubility in aqueous and polar organic media, facilitating seamless integration into synthetic workflows for medicinal chemistry and drug discovery applications.
(3,3-Difluoropiperidin-4-yl)methanol hydrochloride serves as a valuable building block in medicinal chemistry, enabling the introduction of a difluorinated piperidine motif with enhanced metabolic stability and modulated basicity. The hydrochloride salt ensures excellent bench stability and solubility, facilitating straightforward handling and purification. It functions as a key intermediate in the synthesis of bioactive heterocycles, particularly in projects requiring constrained, fluorinated scaffolds for improved pharmacokinetic profiles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: