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3-(Methoxymethyl)-1-methyl-1H-pyrazole-5-carboxylic acid

  • CAS No. 1783796-51-9

  • Cat. No. CS-0169540
  • Molecule weight170.17
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Methoxymethyl)-1-methyl-1H-pyrazole-5-carboxylic acid|CS-0169540

Structure of 1783796-51-9

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General Information

  • CAS No. 1783796-51-9
  • Cat. No. CS-0169540
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂O₃
  • Molecular Weight 170.17
  • Synonym(s) 5-(methoxymethyl)-2-methyl-pyrazole-3-carboxylic acid
  • SMILES O=C(C1=CC(COC)=NN1C)O

Description

This pyrazole carboxylic acid features a methoxymethyl group at the 3-position and a methyl substituent at nitrogen, delivering enhanced solubility and stability. The electron-deficient heterocycle supports efficient coupling reactions, while the carboxylic acid functionality enables direct derivatization in synthetic sequences.

Application

3-(Methoxymethyl)-1-methyl-1H-pyrazole-5-carboxylic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis. Its combination of a carboxylic acid, methylpyrazole, and methoxymethyl group enables diverse functionalization, including derivatization via amide coupling or esterification. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for use in multi-step synthetic campaigns targeting bioactive scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   0.2647
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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