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CS-W001157 4
Total: USD 88.00

(4-(Oxetan-3-yl)phenyl)methanol

  • CAS No. 1781691-11-9

  • Cat. No. CS-0490243
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-(Oxetan-3-yl)phenyl)methanol|CS-0490243

Structure of 1781691-11-9

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General Information

  • CAS No. 1781691-11-9
  • Cat. No. CS-0490243
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₂
  • Molecular Weight 164.20
  • Synonym(s) None
  • SMILES OCC1=CC=C(C=C1)C2COC2

Description

This oxetane-functional phenylmethanol integrates readily into synthetic workflows, offering enhanced solubility and metabolic stability. The oxetan-3-yl group imparts favorable physicochemical properties, while the benzylic alcohol enables straightforward derivatization. Ideal for medicinal chemistry applications requiring robust, flexible scaffolds.

Application

(4-(Oxetan-3-yl)phenyl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to biologically relevant scaffolds. The oxetane ring imparts enhanced metabolic stability and improved solubility, while the benzylic alcohol functionality allows for straightforward derivatization via oxidation, protection, or coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols make it a practical choice for lead optimization and macrocycle construction.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   1.2927
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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