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Structure of 1781658-50-1
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6-Bromo-5-fluoro-1,2,3,4-tetrahydroisoquinoline features a rigid tetrahydroisoquinoline core bearing strategically positioned bromo and fluoro substituents. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions and serves as a key building block for bioactive alkaloid analogs and pharmaceutical intermediates.
6-Bromo-5-fluoro-1,2,3,4-tetrahydroisoquinoline serves as a versatile building block for the synthesis of biologically active heterocycles. Its orthogonal halogenation pattern enables palladium-catalyzed cross-coupling reactions with broad functional group tolerance. The molecule exhibits bench stability and facilitates efficient incorporation into complex scaffolds via standard coupling protocols, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: