Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,1-Dimethylethyl 4-(3-azetidinylmethyl)-1-piperazinecarboxylate

  • CAS No. 1780637-40-2

  • Cat. No. CS-0643057
  • Molecule weight255.36
  • Purity≥95%
  • MDL No.MFCD32710562

*For research and further manufacturing use only, not for direct human use.

1,1-Dimethylethyl 4-(3-azetidinylmethyl)-1-piperazinecarboxylate|CS-0643057

Structure of 1780637-40-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1780637-40-2
  • Cat. No. CS-0643057
  • Purity ≥95%
  • MDL No. MFCD32710562
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₅N₃O₂
  • Molecular Weight 255.36
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CCN(CC1)CC2CNC2

Description

This piperazine derivative features a tert-butyl ester group and a 3-azetidinylmethyl substituent, enabling efficient integration into bioactive molecule scaffolds. The azetidine moiety imparts enhanced metabolic stability and improved membrane permeability, while the piperazine core offers flexible conjugation points for medicinal chemistry optimization.

Application

1,1-Dimethylethyl 4-(3-azetidinylmethyl)-1-piperazinecarboxylate serves as a versatile building block for constructing bioactive heterocyclic scaffolds. The piperazine core enables diverse functionalization, while the azetidine moiety contributes conformational rigidity and enhanced membrane permeability. The tert-butyl ester group provides bench stability and facilitates straightforward deprotection under mild acidic conditions. This compound functions effectively in standard coupling reactions and supports the synthesis of targeted small molecules with optimized physicochemical properties.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.81
  • LogP   0.7585
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1780637-40-2 sigma1780637-40-2 manufacturer1780637-40-2 price1780637-40-2 structure1780637-40-2 SDSbuy 1780637-40-21780637-40-2 supplier1780637-40-2 uses1780637-40-2 molecular weightprice of 1780637-40-21780637-40-2 chemical name formula of 1780637-40-2
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label