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CS-W001157 4
Total: USD 88.00

2-(5-Bromo-2-chlorophenyl)acetic acid

  • CAS No. 177985-34-1

  • Cat. No. CS-W006149
  • Purity≥95%
  • MDL No.MFCD18390584

*For research and further manufacturing use only, not for direct human use.

2-(5-Bromo-2-chlorophenyl)acetic acid|CS-W006149

Structure of 177985-34-1

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General Information

  • CAS No. 177985-34-1
  • Cat. No. CS-W006149
  • Purity ≥95%
  • MDL No. MFCD18390584
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrClO₂
  • Molecular Weight 249.49
  • Synonym(s) None
  • SMILES OC(=O)CC1=C(Cl)C=CC(Br)=C1

Description

2-(5-Bromo-2-chlorophenyl)acetic acid features a brominated and chlorinated aromatic core paired with a carboxylic acid side chain, enabling direct integration into pharmaceutical intermediates. The electron-withdrawing halogens enhance reactivity in coupling processes, while the pendant acid group facilitates derivatization under standard conditions.

Application

2-(5-Bromo-2-chlorophenyl)acetic acid serves as a versatile building block for pharmaceutical intermediates, enabling efficient construction of biologically relevant scaffolds. Its ortho-halogenated aryl core facilitates palladium-catalyzed cross-coupling reactions, while the carboxylic acid functionality supports direct derivatization or activation for peptide coupling. The molecule exhibits excellent bench stability and purification compatibility, making it well-suited for scalable synthesis and process chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.7296
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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