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Structure of 17783-50-5
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8-Methyl-3,8-diazabicyclo[3.2.1]octane dihydrochloride is a sterically hindered, bench-stable nitrogen heterocycle featuring two basic amine centers. This dihydrochloride salt enhances solubility in polar media while maintaining robust reactivity, enabling efficient deprotonation and nucleophilic transformation in synthetic workflows. The methyl substitution at the 8-position modulates electronic properties and steric accessibility, offering tailored performance in catalytic systems and organic synthesis.
8-Methyl-3,8-diazabicyclo[3.2.1]octane dihydrochloride serves as a robust, bench-stable nitrogen base enabling efficient deprotonation and catalytic activation in synthetic transformations. Its constrained bicyclic structure imparts high basicity with minimal nucleophilicity, making it ideal for selective reactions involving acid-sensitive substrates. The dihydrochloride salt enhances solubility and handling, facilitating use in amide coupling, alkylation, and heterocycle formation. Functions reliably in standard organic synthesis workflows requiring controlled basicity and excellent functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: