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CS-W001157 4
Total: USD 88.00

Boronic acid, B-(2-chloro-3-thienyl)-

  • CAS No. 177734-82-6

  • Cat. No. CS-0031356
  • Molecule weight162.40
  • Purity≥97%
  • MDL No.MFCD05662391

*For research and further manufacturing use only, not for direct human use.

Boronic acid, B-(2-chloro-3-thienyl)-|CS-0031356

Structure of 177734-82-6

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General Information

  • CAS No. 177734-82-6
  • Cat. No. CS-0031356
  • Purity ≥97%
  • MDL No. MFCD05662391
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄BClO₂S
  • Molecular Weight 162.40
  • Synonym(s) 5-Chlorothiophen-3-YlboronicAcid
  • SMILES OB(C1=C(SC=C1)Cl)O

Description

This boronate moiety features a chlorine-substituted thiophene ring, enabling direct functionalization in cross-coupling reactions. The electron-deficient heterocycle enhances reactivity while maintaining bench-stable handling under standard conditions.

Application

(2-Chlorothiophen-3-yl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. Its bench-stable nature, tolerance to common functional groups, and compatibility with Suzuki-Miyaura coupling protocols make it a practical reagent for medicinal chemistry and materials synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.0813
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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