4-Bromo-2-chloro-5-fluorobenzoic acid

Name: 4-Bromo-2-chloro-5-fluorobenzoic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 177480-81-8
Cat. No. CS-W002575
Purity≥97%
MDL No.MFCD00236589

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-chloro-5-fluorobenzoic acid|CS-W002575

Structure of 177480-81-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 177480-81-8
Cat. No. CS-W002575
Purity ≥97%
MDL No. MFCD00236589
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₃BrClFO₂
Molecular Weight 253.45
Synonym(s) None
SMILES OC(=O)c1cc(F)c(cc1Cl)Br

Description

4-Bromo-2-chloro-5-fluorobenzoic acid features a trifluorinated aromatic core with orthogonal halogen handles enabling selective cross-coupling. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and functional materials, offering enhanced reactivity under standard conditions.

Application

4-Bromo-2-chloro-5-fluorobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The ortho-halogen substitution pattern facilitates sequential derivatization, while the carboxylic acid group allows for direct amidation, esterification, or salt formation. Its bench-stable crystalline form ensures ease of handling and purification, making it ideal for multi-step synthetic sequences requiring precise regiocontrol and functional group compatibility.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 37.3
LogP 2.9398
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-Bromo-2-chloro-5-fluorobenzoic acid sigma4-Bromo-2-chloro-5-fluorobenzoic acid manufacturer4-Bromo-2-chloro-5-fluorobenzoic acid price4-Bromo-2-chloro-5-fluorobenzoic acid structure4-Bromo-2-chloro-5-fluorobenzoic acid SDSbuy 4-Bromo-2-chloro-5-fluorobenzoic acid4-Bromo-2-chloro-5-fluorobenzoic acid supplier4-Bromo-2-chloro-5-fluorobenzoic acid uses4-Bromo-2-chloro-5-fluorobenzoic acid molecular weightprice of 4-Bromo-2-chloro-5-fluorobenzoic acid4-Bromo-2-chloro-5-fluorobenzoic acid chemical name formula of 4-Bromo-2-chloro-5-fluorobenzoic acid

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromo-2-chloro-5-fluorobenzoic acid

CAS No. 177480-81-8

Recommended Products