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CS-W001157 4
Total: USD 88.00

(3-(Trimethylsilyl)phenyl)boronic acid

  • CAS No. 177171-16-3

  • Cat. No. CS-W010668
  • Purity≥97%
  • MDL No.MFCD03093884

*For research and further manufacturing use only, not for direct human use.

(3-(Trimethylsilyl)phenyl)boronic acid|CS-W010668

Structure of 177171-16-3

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General Information

  • CAS No. 177171-16-3
  • Cat. No. CS-W010668
  • Purity ≥97%
  • MDL No. MFCD03093884
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅BO₂Si
  • Molecular Weight None
  • Synonym(s) 3-Trimethylsilylbenzeneboronic Acid
  • SMILES C[Si](C)(C)C1=CC=CC(=C1)B(O)O

Description

This boronate moiety features a trimethylsilyl group that enhances stability and solubility in organic media. It integrates readily into Suzuki-Miyaura coupling reactions under standard conditions, delivering arylated products with high fidelity. The para-silyl substitution enables orthogonal protection and selective deprotection, streamlining complex molecule assembly.

Synthesis

  • Route1
    • null|null
      121-43-7
    • In-stock
      (3-BRomophenyl)trimethylsilane|CS-0158141
      17878-47-6
    • null|null
      594-19-4
    • ~85%
    • In-stock
      (3-(Trimethylsilyl)phenyl)boronic acid|CS-W010668
      177171-16-3

    References

    • Burn, Paul Leslie; Samuel, Ifor David William; Cumpstey, Neil Patent: US2008/211391 A1, 2008 ;
  • Route2

    References

    • Molecular Crystals and Liquid Crystals, , vol. 444, p. 95 - 101
  • Route3
    • null|null
      97-94-9
    • In-stock
      (3-BRomophenyl)trimethylsilane|CS-0158141
      17878-47-6
    • ~%
    • In-stock
      (3-(Trimethylsilyl)phenyl)boronic acid|CS-W010668
      177171-16-3

    References

    • Molecular Crystals and Liquid Crystals, , vol. 444, p. 95 - 101

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.0884
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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