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CS-W001157 4
Total: USD 88.00

6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1(2H)-one

  • CAS No. 1769-84-2

  • Cat. No. CS-0150349
  • Purity≥98%
  • MDL No.MFCD10698841
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1(2H)-one|CS-0150349

Structure of 1769-84-2

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Description

6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1(2H)-one features a fused tricyclic core with a methoxy group at the 6-position and a phenyl substituent at C2, conferring enhanced electron density and solubility. This scaffold integrates readily into synthetic routes for bioactive heterocycles and serves as a key intermediate in medicinal chemistry campaigns targeting neuroactive compounds.

Application

6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1(2H)-one serves as a versatile scaffold for medicinal chemistry and natural product synthesis. Its fused tetralin core exhibits bench stability and tolerates diverse functional groups, enabling straightforward derivatization via electrophilic substitution, hydrogenation, or coupling reactions. The methoxy and ketone functionalities provide handles for further modification, while the phenyl substituent enhances structural rigidity and π-stacking potential in target engagement studies.

General Information

  • CAS No. 1769-84-2
  • Cat. No. CS-0150349
  • Purity ≥98%
  • MDL No. MFCD10698841
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₆O₂
  • Molecular Weight 252.31
  • Synonym(s) 6-Methoxy-2-phenyl-tetralone
  • SMILES COC1=CC=C2C(=C1)CCC(C3=CC=CC=C3)C2=O

Computational Chemistry Data

  • TPSA   26.3
  • LogP   3.6079
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

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