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Structure of 1769-84-2
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6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1(2H)-one features a fused tricyclic core with a methoxy group at the 6-position and a phenyl substituent at C2, conferring enhanced electron density and solubility. This scaffold integrates readily into synthetic routes for bioactive heterocycles and serves as a key intermediate in medicinal chemistry campaigns targeting neuroactive compounds.
6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1(2H)-one serves as a versatile scaffold for medicinal chemistry and natural product synthesis. Its fused tetralin core exhibits bench stability and tolerates diverse functional groups, enabling straightforward derivatization via electrophilic substitution, hydrogenation, or coupling reactions. The methoxy and ketone functionalities provide handles for further modification, while the phenyl substituent enhances structural rigidity and π-stacking potential in target engagement studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: