Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid

  • CAS No. 176389-60-9

  • Cat. No. CS-0101340
  • Purity≥97%
  • MDL No.MFCD27946223

*For research and further manufacturing use only, not for direct human use.

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid|CS-0101340

Structure of 176389-60-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 176389-60-9
  • Cat. No. CS-0101340
  • Purity ≥97%
  • MDL No. MFCD27946223
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₅F₃N₂O₂
  • Molecular Weight 230.14
  • Synonym(s) None
  • SMILES O=C(C1=CC=CC(C2(N=N2)C(F)(F)F)=C1)O

Description

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid is a photoactivatable probe featuring a trifluoromethyl-substituted diazirine ring conjugated to a benzoic acid moiety. This structure enables site-specific, UV-induced covalent labeling of proximal biomolecules. The electron-withdrawing trifluoromethyl group enhances diazirine stability while maintaining reactivity under standard irradiation conditions. The carboxylic acid functionality allows straightforward conjugation via amide bond formation, facilitating integration into peptides, proteins, or bioconjugates for crosslinking studies.

Application

3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid serves as a versatile photoreactive probe for covalent labeling of biomolecules. The trifluoromethyl-substituted diazirine moiety enables efficient UV-induced formation of reactive nitrenes, facilitating site-specific protein and nucleic acid crosslinking. The carboxylic acid group provides a handle for conjugation via standard amide coupling, enhancing solubility and enabling integration into peptide and small-molecule scaffolds. Its bench-stable nature and compatibility with diverse reaction conditions make it suitable for routine use in chemical biology workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H228-H315-H319
Precautionary Statements : P210-P240-P241-P264-P280-P302+P352-P362+P364-P370+P378

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   62.02
  • LogP   2.5657
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 176389-60-9 sigma176389-60-9 manufacturer176389-60-9 price176389-60-9 structure176389-60-9 SDSbuy 176389-60-9176389-60-9 supplier176389-60-9 uses176389-60-9 molecular weightprice of 176389-60-9176389-60-9 chemical name formula of 176389-60-9
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label