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CS-W001157 4
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4-Pyrazol-1-yl-phenylamine

  • CAS No. 17635-45-9

  • Cat. No. CS-W022235
  • Purity≥98%
  • MDL No.MFCD00626298

*For research and further manufacturing use only, not for direct human use.

4-Pyrazol-1-yl-phenylamine|CS-W022235

Structure of 17635-45-9

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General Information

  • CAS No. 17635-45-9
  • Cat. No. CS-W022235
  • Purity ≥98%
  • MDL No. MFCD00626298
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉N₃
  • Molecular Weight 159.19
  • Synonym(s) 4-(1H-Pyrazol-1-yl)aniline
  • SMILES C2=C([N]1N=CC=C1)C=CC(=C2)N

Description

4-Pyrazol-1-yl-phenylamine features a pyrazole ring directly linked to a phenylamine moiety, creating a rigid, electron-rich scaffold ideal for conjugation in pharmaceutical intermediates. This structure enables effective integration into bioactive molecules through amine functionalization, offering enhanced solubility and stability under standard conditions.

Application

4-Pyrazol-1-yl-phenylamine serves as a versatile building block for constructing bioactive heterocycles and functionalized anilines. Its pyrazole-aryl amine architecture enables direct incorporation into pharmaceutical scaffolds via standard coupling reactions. The molecule exhibits good bench stability, moderate solubility in common organic solvents, and tolerance to a range of reaction conditions, facilitating straightforward purification and integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   1.4545
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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