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CS-W001157 4
Total: USD 88.00

(E)-3-(3-Methoxyphenyl)acrylic acid

  • CAS No. 17570-26-2

  • Cat. No. CS-0166751
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(E)-3-(3-Methoxyphenyl)acrylic acid|CS-0166751

Structure of 17570-26-2

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General Information

  • CAS No. 17570-26-2
  • Cat. No. CS-0166751
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₃
  • Molecular Weight 178.18
  • Synonym(s) TRANS-3-METHOXYCINNAMIC ACID
  • SMILES O=C(O)/C=C/C1=CC=CC(OC)=C1

Description

(E)-3-(3-Methoxyphenyl)acrylic acid features a conjugated system with a para-methoxy-substituted phenyl ring, enhancing electron delocalization and stability. This bench-stable enone scaffold integrates readily into synthetic routes for bioactive compounds, offering predictable reactivity in coupling and cyclization processes under standard conditions.

Application

(E)-3-(3-Methoxyphenyl)acrylic acid serves as a versatile building block for synthesizing conjugated systems and bioactive heterocycles. Its well-defined geometry and stability enable reliable use in Michael additions, Diels–Alder reactions, and transition-metal-catalyzed couplings. The methoxy group enhances solubility and provides a handle for further functionalization, while the carboxylic acid facilitates direct derivatization or salt formation. This compound is particularly valuable for medicinal chemistry campaigns targeting kinase inhibitors and anti-inflammatory agents.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.793
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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