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Structure of 175204-80-5
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3-Amino-4-(trifluoromethyl)pyridine features a strategically positioned trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the amino functionality enables direct coupling in C–N bond formation. This scaffold integrates readily into pharmaceutical intermediates and functional materials under standard conditions.
3-Amino-4-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized pyridine scaffolds. The amino group facilitates electrophilic substitution and transition-metal-catalyzed coupling reactions, while the electron-withdrawing trifluoromethyl moiety enhances metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with common protecting group strategies streamline synthesis of kinase inhibitors and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: