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3-Benzyl-5-bromopyrazin-2-amine

  • CAS No. 174680-55-8

  • Cat. No. CS-0140965
  • Molecule weight264.12
  • Purity≥95%
  • MDL No.MFCD03453134

*For research and further manufacturing use only, not for direct human use.

3-Benzyl-5-bromopyrazin-2-amine|CS-0140965

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General Information

  • CAS No. 174680-55-8
  • Cat. No. CS-0140965
  • Purity ≥95%
  • MDL No. MFCD03453134
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀BrN₃
  • Molecular Weight 264.12
  • Synonym(s) 5-BROMO-3-(PHENYLMETHYL)-PYRAZINAMINE
  • SMILES NC1=NC=C(Br)N=C1CC2=CC=CC=C2

Description

3-Benzyl-5-bromopyrazin-2-amine features a brominated pyrazine core paired with a benzyl substituent, delivering enhanced electron-deficient character for cross-coupling applications. This bench-stable compound integrates readily into pharmaceutical scaffolds and enables efficient access to functionalized heterocycles under standard conditions.

Application

3-Benzyl-5-bromopyrazin-2-amine serves as a versatile building block for constructing pyrazine-based heterocycles in medicinal chemistry and materials science. The bromo group enables palladium-catalyzed cross-coupling reactions, while the amine functionality offers sites for derivatization. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   2.4121
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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