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CS-W001157 4
Total: USD 88.00

5-Amino-3-methyl-1,2,4-thiadiazole

  • CAS No. 17467-35-5

  • Cat. No. CS-0038032
  • Molecule weight115.16
  • Purity≥97%
  • MDL No.MFCD01114751

*For research and further manufacturing use only, not for direct human use.

5-Amino-3-methyl-1,2,4-thiadiazole|CS-0038032

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General Information

  • CAS No. 17467-35-5
  • Cat. No. CS-0038032
  • Purity ≥97%
  • MDL No. MFCD01114751
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅N₃S
  • Molecular Weight 115.16
  • Synonym(s) 5-Amino-3-Methyl-1,3,4-Thiadiazole
  • SMILES CC1=NSC(=N1)N

Description

5-Amino-3-methyl-1,2,4-thiadiazole features a fused heterocyclic core with complementary amino and methyl substituents that enhance solubility and reactivity. This bench-stable compound integrates readily into synthetic pathways requiring electron-rich thiadiazole scaffolds.

Application

5-Amino-3-methyl-1,2,4-thiadiazole serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its amino and methyl groups enable diverse functionalization, while the 1,2,4-thiadiazole core provides enhanced metabolic stability and hydrogen-bonding capacity. The compound exhibits good bench stability and facilitates efficient coupling reactions, making it suitable for constructing bioactive scaffolds and advanced synthetic intermediates.

Synthesis

  • Route1
    • null|null
      333-20-0
    • 2-Chloroacetamidine|CS-M2910
      20846-52-0
    • ~32%
    • In-stock
      5-Amino-3-methyl-1,2,4-thiadiazole|CS-0038032
      17467-35-5

    References

    • LegoChem Biosciences, Inc.; CHO, Young Lag; YUN, Joung Yul; PARK, Chul Soon; CHAE, Sang Eun; LEE, Hyang Sook; OH, Kyuman; HEO, Hye Jin; KANG, Dae Hyuck; YANG, Young Jae; KWON, Hyun Jin; PARK, Tae Kyo; WOO, Sung Ho; KIM, Yong Zu Patent: EP2706062 A2, 2014 ; Location in patent: Paragraph 0199 ;
  • Route2
    • null|null
      118493-85-9
    • ~%
    • In-stock
      5-Amino-3-methyl-1,2,4-thiadiazole|CS-0038032
      17467-35-5

    References

    • US5773624 A1, ;
  • Route3
    • null|null
      124-42-5
    • null|null
      333-20-0
    • ~%
    • In-stock
      5-Amino-3-methyl-1,2,4-thiadiazole|CS-0038032
      17467-35-5

    References

    • Gazzetta Chimica Italiana, , vol. 107, p. 1 - 5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   0.42872
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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