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(R)-2-Cyclopentyl-2-hydroxyacetic acid

  • CAS No. 174603-03-3

  • Cat. No. CS-0533474
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-2-Cyclopentyl-2-hydroxyacetic acid|CS-0533474

Structure of 174603-03-3

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General Information

  • CAS No. 174603-03-3
  • Cat. No. CS-0533474
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O₃
  • Molecular Weight 144.17
  • Synonym(s) (2R)-2-cyclopentyl-2-hydroxyacetic acid
  • SMILES OC([C@@H](C1CCCC1)O)=O

Description

(R)-2-Cyclopentyl-2-hydroxyacetic acid is a chiral α-hydroxy acid featuring a cyclopentyl group at the α-position, offering enhanced steric and electronic modulation. This bench-stable, moisture-tolerant compound integrates readily into asymmetric synthesis workflows, serving as a key building block for pharmaceutical intermediates and bioactive molecule scaffolds.

Application

(R)-2-Cyclopentyl-2-hydroxyacetic acid serves as a valuable chiral building block for the synthesis of bioactive molecules and pharmaceutical intermediates. Its stereogenic center enables enantioselective transformations, while the α-hydroxy carboxylic acid functionality offers versatility in coupling reactions, derivatization, and metal coordination. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   0.6221
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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