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Amino-Tri-(carboxyethoxymethyl)-methane

  • CAS No. 174362-95-9

  • Cat. No. CS-0066369
  • Molecule weight337.32
  • Purity≥97%
  • MDL No.MFCD31615450

*For research and further manufacturing use only, not for direct human use.

Amino-Tri-(carboxyethoxymethyl)-methane|CS-0066369

Structure of 174362-95-9

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General Information

  • CAS No. 174362-95-9
  • Cat. No. CS-0066369
  • Purity ≥97%
  • MDL No. MFCD31615450
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₃NO₉
  • Molecular Weight 337.32
  • Synonym(s) None
  • SMILES NC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O

Description

Amino-Tri-(carboxyethoxymethyl)-methane features three carboxyethoxymethyl groups anchored to a central methane core, delivering exceptional water solubility and multidentate coordination capacity. This trifunctional scaffold enables efficient conjugation in bioconjugation workflows and serves as a robust linker for chelating metal ions in diagnostic and therapeutic applications.

Application

Amino-tri(carboxyethoxymethyl)methane serves as a versatile tetradentate ligand scaffold, enabling efficient metal coordination in catalytic systems. Its three carboxylic acid groups and one primary amine provide robust chelation capacity, facilitating stability in aqueous and protic environments. The molecule exhibits excellent bench stability and simplifies purification through crystallization or ion-exchange chromatography. Functions effectively in transition metal-catalyzed cross-coupling and asymmetric synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   165.61
  • LogP   -0.8422
  • H_Acceptors   7
  • H_Donors   4
  • Rotatable_Bonds   15

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