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Structure of 1736-06-7
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This trifluoromethyl ketone features a para-methyl-substituted aryl group, delivering enhanced lipophilicity and metabolic stability. The electron-withdrawing trifluoromethyl moiety strengthens carbonyl electrophilicity, enabling efficient nucleophilic addition in synthetic transformations. Bench-stable and moisture-tolerant, it serves as a key building block for pharmaceutical intermediates and functional materials.
2,2,2-Trifluoro-1-(m-tolyl)ethanone serves as a versatile fluorinated ketone building block in synthetic organic chemistry. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. The compound facilitates efficient Friedel–Crafts acylation and acts as a key intermediate in the synthesis of fluorinated heterocycles and bioactive scaffolds. Bench-stable and readily purified by recrystallization, it offers reliable functionality in standard reaction workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: