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Structure of 173443-43-1
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Diethyl (4-iodobenzyl)phosphonate features a para-iodinated benzyl moiety integrated with a phosphonate ester group, enabling direct functionalization in cross-coupling reactions. This bench-stable reagent facilitates efficient P–C bond formation under palladium catalysis, serving as a key intermediate in the synthesis of bioactive phosphonate analogs and pharmaceutical building blocks.
Diethyl (4-iodobenzyl)phosphonate serves as a versatile building block for C–C bond formation via Negishi and Suzuki-Miyaura coupling reactions. The iodide group enables reliable palladium-catalyzed cross-coupling, while the phosphonate moiety offers stability and compatibility with standard synthetic protocols. Its bench-stable nature and ease of purification facilitate integration into multi-step sequences for heterocyclic and pharmaceutical scaffold synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H412
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Precautionary Statements : P264-P270-P273-P330-P501
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Lot numbers can be found on the outside label of a product: