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CS-W001157 4
Total: USD 88.00

Spiro[2.5]octane-1-carboxylic acid

  • CAS No. 17202-86-7

  • Cat. No. CS-0055830
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Spiro[2.5]octane-1-carboxylic acid|CS-0055830

Structure of 17202-86-7

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Description

Spiro[2.5]octane-1-carboxylic acid features a rigid, three-dimensional spirocyclic core that imparts exceptional conformational stability and spatial control. This scaffold integrates a carboxylic acid group at the bridgehead position, enabling direct coupling in peptide synthesis or conjugation strategies without epimerization risk. The molecule's steric shielding enhances metabolic resistance and improves membrane permeability in bioactive compound design.

Application

Spiro[2.5]octane-1-carboxylic acid serves as a rigid, three-dimensional building block for medicinal chemistry and materials science applications. Its spirocyclic core imparts conformational stability and enhances metabolic resistance, while the carboxylic acid group enables facile derivatization via amide, ester, or salt formation. The compound exhibits good bench stability and is compatible with standard coupling protocols, facilitating integration into complex molecular architectures.

General Information

  • CAS No. 17202-86-7
  • Cat. No. CS-0055830
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄O₂
  • Molecular Weight 154.21
  • Synonym(s) None
  • SMILES C1CCC2(CC1)CC2C(=O)O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.0414
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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