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Structure of 17202-86-7
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Spiro[2.5]octane-1-carboxylic acid features a rigid, three-dimensional spirocyclic core that imparts exceptional conformational stability and spatial control. This scaffold integrates a carboxylic acid group at the bridgehead position, enabling direct coupling in peptide synthesis or conjugation strategies without epimerization risk. The molecule's steric shielding enhances metabolic resistance and improves membrane permeability in bioactive compound design.
Spiro[2.5]octane-1-carboxylic acid serves as a rigid, three-dimensional building block for medicinal chemistry and materials science applications. Its spirocyclic core imparts conformational stability and enhances metabolic resistance, while the carboxylic acid group enables facile derivatization via amide, ester, or salt formation. The compound exhibits good bench stability and is compatible with standard coupling protocols, facilitating integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: