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Structure of 17175-16-5
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Methyl (4-nitrophenyl) carbonate is a bench-stable, moisture-tolerant reagent featuring a para-nitro group that enhances electrophilicity at the carbonyl center. This compound facilitates efficient O-alkylation of phenols and alcohols under mild conditions, delivering protected derivatives with high selectivity. Its stability simplifies handling in synthetic workflows.
Methyl (4-nitrophenyl) carbonate serves as a stable, bench-ready carbonylating agent for the synthesis of esters and carbamates. Its mild reactivity enables efficient O- and N-alkylation under ambient conditions, with the 4-nitrophenyl leaving group facilitating clean displacement. The compound exhibits excellent functional group tolerance and is readily purified by flash chromatography, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: