Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Methyl-5-phenylisoxazole-4-carboxylic acid

  • CAS No. 17153-21-8

  • Cat. No. CS-W021966
  • Molecule weight203.19
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methyl-5-phenylisoxazole-4-carboxylic acid|CS-W021966

Structure of 17153-21-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 17153-21-8
  • Cat. No. CS-W021966
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉NO₃
  • Molecular Weight 203.19
  • Synonym(s) 3-methyl-5-phenyl-4-isoxazolecarboxylic acid
  • SMILES O=C(C1=C(C2=CC=CC=C2)ON=C1C)O

Description

3-Methyl-5-phenylisoxazole-4-carboxylic acid features a rigid, electron-deficient isoxazole core paired with a phenyl substituent and a carboxylic acid handle. This combination enables direct integration into bioconjugation workflows and serves as a key scaffold in the development of functionalized heterocycles for medicinal chemistry applications.

Application

3-Methyl-5-phenylisoxazole-4-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its structure combines a stable isoxazole core with orthogonal functional groups, enabling direct coupling reactions and derivatization under standard conditions. The carboxylic acid moiety facilitates amide bond formation and salt generation, while the methyl and phenyl substituents provide steric and electronic tuning for scaffold diversification. Bench-stable and readily purified by recrystallization, it functions as a reliable intermediate in the synthesis of bioactive compounds and functional polymers.

Synthesis

  • Route1
    • null|null
      92029-29-3
    • ~93%
    • In-stock
      3-Methyl-5-phenylisoxazole-4-carboxylic acid|CS-W021966
      17153-21-8

    References

    • Cheng, Huimin; Wan, Junting; Lin, Meng-I; Liu, Yingxue; Lu, Xiaoyun; Liu, Jinsong; Xu, Yong; Chen, Jianxin; Tu, Zhengchao; Cheng, Yih-Shyun E.; Ding, Ke Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 2144 - 2153
  • Route2
    • null|null
      569-37-9
    • ~%
    • In-stock
      3-Methyl-5-phenylisoxazole-4-carboxylic acid|CS-W021966
      17153-21-8

    References

    • Gazzetta Chimica Italiana, , vol. 45 I, p. 466
  • Route3
    • null|null
      98-88-4
    • ~%
    • In-stock
      3-Methyl-5-phenylisoxazole-4-carboxylic acid|CS-W021966
      17153-21-8

    References

    • Chemische Berichte, , vol. 42, p. 3919

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.33
  • LogP   2.34822
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 17153-21-8 sigma17153-21-8 manufacturer17153-21-8 price17153-21-8 structure17153-21-8 SDSbuy 17153-21-817153-21-8 supplier17153-21-8 uses17153-21-8 molecular weightprice of 17153-21-817153-21-8 chemical name formula of 17153-21-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label