Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone

  • CAS No. 171364-81-1

  • Cat. No. CS-0155101
  • Purity≥97%
  • MDL No.MFCD05863922

*For research and further manufacturing use only, not for direct human use.

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone|CS-0155101

Structure of 171364-81-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 171364-81-1
  • Cat. No. CS-0155101
  • Purity ≥97%
  • MDL No. MFCD05863922
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉BO₃
  • Molecular Weight 246.11
  • Synonym(s) 4-Acetylphenylboronic acid, pinacol ester
  • SMILES CC(=O)C1=CC=C(C=C1)B2OC(C)(C)C(C)(C)O2

Description

This boronate ester integrates a phenyl ketone moiety with a stable tetramethyl-1,3,2-dioxaborolane group, enabling efficient Suzuki-Miyaura coupling under standard conditions. The electron-deficient arylboronate facilitates rapid cross-coupling, while the bench-stable, moisture-tolerant structure simplifies handling and storage in synthetic workflows.

Application

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. Its stable boronate ester functionality enables efficient C–C bond formation under mild conditions, with excellent functional group tolerance and bench stability. The acetyl group provides orthogonal reactivity for downstream modifications, making it ideal for constructing complex aryl ketone scaffolds in medicinal chemistry and materials synthesis.

Synthesis

  • Route1
    • null|null
      99-91-2
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • ~96%
    • In-stock
      1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone|CS-0155101
      171364-81-1

    References

    • Chow, Wing Kin; Yuen, On Ying; So, Chau Ming; Wong, Wing Tak; Kwong, Fuk Yee Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3543 - 3548
  • Route2

    References

    • Wang, Lianhui; Li, Jingya; Cui, Xiuling; Wu, Yusheng; Zhu, Zhiwu; Wu, Yangjie Advanced Synthesis and Catalysis, 2010 , vol. 352, # 11-12 p. 2002 - 2010
  • Route3
    • 1-(4-Aminophenyl)ethanone Clenbuterol Impurity|CS-0229065
      99-92-3
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • ~70%
    • In-stock
      1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone|CS-0155101
      171364-81-1

    References

    • Zhang, Jie; Wang, Xiaolong; Yu, Haitao; Ye, Jiahai Synlett, 2012 , vol. 23, # 9 p. 1394 - 1396

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.53
  • LogP   2.1884
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 171364-81-1 sigma171364-81-1 manufacturer171364-81-1 price171364-81-1 structure171364-81-1 SDSbuy 171364-81-1171364-81-1 supplier171364-81-1 uses171364-81-1 molecular weightprice of 171364-81-1171364-81-1 chemical name formula of 171364-81-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label