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CS-W001157 4
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(R)-3-Hydroxy-2-phenylpropanoic acid

  • CAS No. 17126-67-9

  • Cat. No. CS-0163148
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-3-Hydroxy-2-phenylpropanoic acid|CS-0163148

Structure of 17126-67-9

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General Information

  • CAS No. 17126-67-9
  • Cat. No. CS-0163148
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight 166.17
  • Synonym(s) (R)-tropic acid
  • SMILES O=C(O)[C@H](C1=CC=CC=C1)CO

Description

(R)-3-Hydroxy-2-phenylpropanoic acid features a chiral center at the C3 position, delivering high enantioselectivity in asymmetric synthesis. The hydroxyl group enables derivatization for bioactive molecule construction, while the aromatic phenyl moiety imparts stability and enhanced solubility in organic media. This configuration supports efficient incorporation into complex scaffolds under standard bench conditions.

Application

(R)-3-Hydroxy-2-phenylpropanoic acid serves as a key chiral building block for synthesizing bioactive molecules and pharmaceutical intermediates. Its well-defined stereochemistry enables reliable asymmetric transformations, while the hydroxyl and carboxylic acid functionalities support diverse functional group interconversions. The compound exhibits good bench stability and facilitates efficient derivatization in standard organic synthesis workflows.

Synthesis

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    • ~%
    • In-stock
      (R)-3-Hydroxy-2-phenylpropanoic acid|CS-0163148
      17126-67-9

    References

    • Guanti, Giuseppe; Narisano, Enrica; Podgorski, Tadeusz; Thea, Sergio; Williams, Andrew Tetrahedron, 1990 ,  vol. 46,  # 20  p. 7081 - 7092

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   0.8471
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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