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CS-W001157 4
Total: USD 88.00

2-Phenyl-1,3-dioxan-5-ol

  • CAS No. 1708-40-3

  • Cat. No. CS-0156338
  • Purity≥97%
  • MDL No.MFCD00047504

*For research and further manufacturing use only, not for direct human use.

2-Phenyl-1,3-dioxan-5-ol|CS-0156338

Structure of 1708-40-3

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General Information

  • CAS No. 1708-40-3
  • Cat. No. CS-0156338
  • Purity ≥97%
  • MDL No. MFCD00047504
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₃
  • Molecular Weight 180.20
  • Synonym(s) 5-Hydroxy-2-phenyl-1,3-dioxane
  • SMILES C1=CC=C(C=C1)C2OCC(CO2)O

Description

cis-2-phenyl-1,3-dioxan-5-ol reacts with triphenylphosphine-carbon tetrabromide to yield cis-4-bromomethyl-2-phenyl-1,3-dioxolan, its trans-diastereoisomer and trans-5-bromo-2-phenyl-1,3-dioxan.2-Phenyl-1,3-dioxan-5-ol can be used as a starting material in the synthesis of 5-benzyloxy1,3-dioxan-2-one (a carbonate of glycerol monomer). It undergoes ring-opening polymerization with -caprolactone in presence of tin(II) 2-ethylhexanoate (Sn(oct)2).

Synthesis

  • Route1
    • null|null
      100-52-7
    • In-stock
      Glycerol|CS-6964
      56-81-5
    • ~67%
    • In-stock
      2-Phenyl-1,3-dioxan-5-ol|CS-0156338
      1708-40-3

    References

    • Cassel, Stephanie; Debaig, Catherine; Benvegnu, Thierry; Chaimbault, Patrick; Lafosse, Michel; Plusquellec, Daniel; Rollin, Patrick European Journal of Organic Chemistry, 2001 , # 5 p. 875 - 896
  • Route2
    • null|null
      104-15-4
    • ~%
    • In-stock
      2-Phenyl-1,3-dioxan-5-ol|CS-0156338
      1708-40-3

    References

    • US5608110 A1, ;
  • Route3
    • null|null
      100-52-7
    • In-stock
      Glycerol|CS-6964
      56-81-5
    • ~47%
    • (2-Phenyl-1,3-dioxolan-4-yl)methanol|CS-0700250
      1708-39-0
    • (2-Phenyl-1,3-dioxolan-4-yl)methanol|CS-0700250
      1708-39-0
    • In-stock
      2-Phenyl-1,3-dioxan-5-ol|CS-0156338
      1708-40-3

    References

    • Carlsen, Per H. J.; Sorbye, Karsten; Ulven, Trond; Aasbo, Kari Acta Chemica Scandinavica, 1996 , vol. 50, # 2 p. 185 - 187

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.69
  • LogP   1.0929
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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