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Structure of 170462-68-7
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This trifluoromethylated amino acid derivative features a tert-butoxycarbonyl-protected amine and a sterically hindered, electron-deficient trifluoromethyl group. The combination imparts enhanced metabolic stability and favorable lipophilic character, enabling efficient incorporation into peptide-based scaffolds under standard coupling conditions.
2-{[(tert-butoxy)carbonyl]amino}-3,3,3-trifluoro-2-methylpropanoic acid serves as a stable, bench-ready building block for the synthesis of trifluoromethylated amino acid derivatives. Its tert-butyl carbamate (Boc) protection ensures compatibility with standard peptide coupling protocols, while the trifluoromethyl and methyl groups provide enhanced metabolic stability and steric definition. The carboxylic acid functionality enables straightforward activation and incorporation into diverse scaffolds, including heterocycles and bioactive peptides.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: