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CS-W001157 4
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2-(((Tert-butoxycarbonyl)(methyl)amino)methyl)benzoic acid

  • CAS No. 1699713-02-4

  • Cat. No. CS-0515528
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(((Tert-butoxycarbonyl)(methyl)amino)methyl)benzoic acid|CS-0515528

Structure of 1699713-02-4

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General Information

  • CAS No. 1699713-02-4
  • Cat. No. CS-0515528
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉NO₄
  • Molecular Weight 265.30
  • Synonym(s) None
  • SMILES CN(CC1=CC=CC=C1C(=O)O)C(=O)OC(C)(C)C

Description

This protected amino acid derivative features a tert-butoxycarbonyl-methylamino side chain appended to a benzoic acid core. The Boc group provides orthogonal protection for amine functionalities, enabling selective deprotection during peptide synthesis. The molecule exhibits enhanced solubility and stability under standard bench conditions, facilitating handling in multi-step organic transformations.

Application

2-(((Tert-butoxycarbonyl)(methyl)amino)methyl)benzoic acid serves as a versatile building block for peptide and heterocyclic synthesis, offering orthogonal protection of both amine and carboxylic acid functionalities. The Boc-methylamino side chain enables selective deprotection under mild acidic conditions, while the benzoic acid moiety facilitates coupling reactions with amines or alcohols. Its bench-stable nature and compatibility with standard purification methods make it well-suited for multi-step synthetic sequences in medicinal chemistry and API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.7517
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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